Determination

Control

(12)

Control + 10 cariporide

(12)

Control + 20 cariporide

(12)

ZDF

(12)

ZDF + 10 cariporide

(12)

ZDF + 20 cariporide

(12)

Final weight (g)

381 ± 4

370 ± 8

374 ± 5

402 ± 9

386 ± 10

372 ± 11

Blood glucose (mM)

6.2 ± 0.1

6.1 ± 0.1

6.5 ± 0.1

23.4 ± 1.2^*

22.8 ± 0.7^*

20.0 ± 0.1^*

MNCV (m/sec)

56.9 ± 1.1

55.3 ± 1.1

57.1 ± 1.0

45.5 ± 1.2^*

51.4 ± 0.8^*,#

53.7 ± 1.3^*,#

SNCV (m/sec)

45.9± 0.9

45.5 ± 0.9

43.7 ± 0.9

35.9 ± 1.2^*

37.0 ± 0.8^*

41.2 ± 0.4^*,#

Thermal response latency (sec)

10.9 ± 0.4

11.4 ± 0.6

11.8 ± 0.7

18.5 ± 0.6^*

16.9 ± 0.7^*

12.9 ± 0.5^*,#

Tactile response threshold (g)

20.8 ± 1.2

22.0 ± 1.1

18.7 ± 1.2

6.5 ± 0.7^*

7.8 ± 0.3^*

13.0 ± 1.6^*,#